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Chloroquine/Hydroxychloroquine

Posted: Thu Mar 26, 2020 11:48 am
by Netpackrat
We have probably all heard something about this, from the very limited study in France, to the president's touting of same as a possibility, or the dead idiot and his wife who ingested an aquarium cleaning agent because it had a similar chemical name. Drug companies are trying to restrict it to those patients already prescribed it for other ailments, and the governor of at least one state issued an order banning off-label uses of it. There's at least one researcher currently organizing a clinical trial to test it against COVID-19 but they are saying any results are weeks away, at least.

Meanwhile, at least one doctor in NY state appears to have taken matters into his own hands, treated hundreds of confirmed cases with a regimen based off what the French used, and he's claiming some pretty remarkable results:

https://uslibertywire.com/ny-doctor-suc ... tubations/

They are primarily antimalarials, but they are also used to treat lupus which is an autoimmune disorder, so it makes some amount of sense if part of the problem with Coronavirus is that it causes your immune system to overreact. It apparently has some potentially nasty side effects, but they are well known, and it's been in use on humans for decades. I hope production is being ramped up significantly given that it already has Trump's attention. At worst, it isn't useful and we end up making a bunch that we can't use, but otherwise it could be the thing that bridges the gap between where we are now, and when a vaccine finally becomes available. Thought I would share the link since it could be some good news.

Re: Chloroquine/Hydroxychloroquine

Posted: Thu Mar 26, 2020 8:03 pm
by Weetabix
Netpackrat wrote: Thu Mar 26, 2020 11:48 amThey are primarily antimalarials, but they are also used to treat lupus which is an autoimmune disorder, so it makes some amount of sense if part of the problem with Coronavirus is that it causes your immune system to overreact.
Hm. I wonder if they've tried prednisone? When I had Adult Onset Still's Disease (which the doctors told me had my immune system attacking my joints), prednisone had me walking again in about a day.

Re: Chloroquine/Hydroxychloroquine

Posted: Fri Mar 27, 2020 4:49 pm
by Vonz90
I had to take a daily dose Chloroquine on deployment for about a year. About two hours of nausea and headache every morning (more if no opportunity to eat at the same time) - but better than getting malaria.

Re: Chloroquine/Hydroxychloroquine

Posted: Fri Mar 27, 2020 8:32 pm
by Weetabix
Malaria pretty much doesn't go away once you have it, does it?

Re: Chloroquine/Hydroxychloroquine

Posted: Fri Mar 27, 2020 10:10 pm
by Netpackrat
https://townhall.com/tipsheet/sarahlee/ ... e-n2565847

A lot of articles out there slanted against this treatment because Orange Man Bad, but meanwhile other countries appear to be embracing it. A key point seems to be that to be effective, it may need to be used in combination with the other drugs as it was by the doctor in NY, the French study, etc.

Re: Chloroquine/Hydroxychloroquine

Posted: Fri Mar 27, 2020 10:39 pm
by Vonz90
Weetabix wrote: Fri Mar 27, 2020 8:32 pm Malaria pretty much doesn't go away once you have it, does it?
Not a Dr. So IDK. As they explained at the time, the treatment also prevents you from getting it. I took their word on that.

Re: Chloroquine/Hydroxychloroquine

Posted: Fri Mar 27, 2020 10:55 pm
by Netpackrat
According to what I was reading on the stuff, it was so widely used in the last century, that many species of the micro-organisms that cause malaria are now resistant. So it's only effective if you encounter malaria that it still works against.

Re: Chloroquine/Hydroxychloroquine

Posted: Thu Apr 02, 2020 11:04 pm
by Netpackrat

Re: Chloroquine/Hydroxychloroquine

Posted: Fri Apr 10, 2020 8:28 pm
by Netpackrat

Re: Chloroquine/Hydroxychloroquine

Posted: Sat Apr 11, 2020 12:23 am
by Durham68