As I did this, I noticed that the cylinder would become hard to turn/not turn at all. The primer would back out of the pocket after firing, sometimes to the extent that it would require a plastic hammer to get it loose.
Yeah, that's your primer backing out. It's a regular occurrence in low-pressure loads, and you can't get much lower pressure than a primer-only load.
What happens when firing a regular cartridge is that when the firing pin hits the primer, it pushes the cartridge forward before it ignites the primer. There are two different things happening. The tiny bit of flash powder in the primer ignites, but before the main charge lights the primer unseats and goes back to the recoil shield. More pressure as the main charge lights, and the cartridge case slams back against the recoil shield, which re-seats the primer. About that time, the pressure builds more, the cartridge case expands to grip the chamber wall and the bullet releases. By the time you hear the boom, all this is over and pressure returns to normal. The primer is re-seated and the case is again "loose" in the cylinder.
What happens in a primer-only load is that the primer unseats under pressure, but the cartridge doesn't generate enough pressure to slam back against the recoil shield. That ties up the cylinder.
All this to say that primer-only loads routinely tie up the cylinder. I would expect it almost every time even if the cartridge case is empty. There's no pressure tore-seat the primer.
Because we shoot a lot of very low pressure loads in Cowboy Fast Draw, we've developed some special techniques to deal with this issue. The most garage-friendly technique is to drill the flash-hole. I normally use a 5/32 or 3/16 bit to drill out the flash hole. Then I seat a regular primer, put 3 grains of Triple7 powder and seat a wax bullet (this for .45 loads). This load is very safe, it will dent, but not penetrate 1/2 inch plywood. The bullet will fly about 30 yards unimpeded before it runs out of momentum and falls to the ground.It's a very safe load for testing revolvers in a suburban area.